My normal draw weight at full draw is 65#@29.5" for target practice.
On several occasions last year I borrowed a yew warbow from an English friend that was 90#@32" which felt pretty much the same resistance as my target bow, simply the pull was some longer. When trying a 110#@32" the resistance was remarkably higher, but something in my brain saying "dang, that stick will break..." seemed more of a problem than the acctual draw weight. But 110# was my borderline, 120# my whole body said "No!"
I believe a decent shooting technique would be the key, evenmore for the thumb draw.