In the meantime, as you work your way toward brace, ensure extremely accurate width, and then thickness tapering. Checking thickness across the limb every inch or two as well. Be anal about it.
When all those things are accurate, no matter how much character there is, you can't get into too much trouble... and when you brace it, it'll sort of show you how it should look. If that funky spot is only in one limb, don't try to tiller it into a nice arc like you would a straight stave. And don't try to make both limbs look the same.
If it were me, I'd level the handle area in the tree, ignoring whether one tip was higher than the other, pull the string from my string hand fulcrum location, and adjust the strength of the limbs so the hook came straight down. That's how I balance all bows, character or not.
I'm currently working on the most snakey bow I've ever tillered, and it's really slow going, maintaining all proportions accurately as I sneak up to brace height. It's taking forever. But I know when it's finally braced, it'll have a good start with only minor work needed the rest of the way.