Its not about which way you flex the first glue-up, its about how thick the belly/core glue up is when you apply the backing.
Imagine a 10 lam bow. each lam glued in succession. you could make adjustments to side profile with each glue-up and create a very intricate shape to start tillering with, but since a thin lam is not strained much when bent, you would have created very little prestress to help the belly at full draw.