Joe,
Here is my experience with bamboo--if you sand them down, you can sand smooth the nodes, but only after you straighten them. I didn't know what I was doing when I started, so I just made a bunch and shot them to see which matched well with the bow I had. I found that a wide variety of weights shot about the same, but the really stiff ones didn't. I also found a pretty good correlation between diameter and stiffness. When you spine them, they will be differently stiff depending how you turn them, so put the stiff side of the arrow against the bow when you make your nock. drill a hole where you want the nock and then cut down to it. If you look on the how to at the top of this page, it works really well. Wrap at the base of the nock. If I can do it, anyone can.