Can't say for sure, but I bet you can pull it off. I've made 48" hickory and maple D bows that draw 40-45 and have drawn them out to 27". Problem was, the set was excessive and these bows had short lives. If you keep it at 22" of draw and keep your inch of width, Osage seems like a good choice to pull it off with. There are lots of Plains style bows that would be in that range that I'm sure draw that amount. Maybe you'd consider sinew backing it to make sure?